This is the digital workspace for coordination and discussion on the Belgian chapter of the Open Insulin project. The global project is being executed in local biohacking labs across the globe, with the researchers collaborating online.

Physical meetups happen every two weeks on Wednesdays at 8pm CET in the ReaGent lab in Ghent. Everyone is welcome to join, see the notes for the next date. Calls with the international team happen every two weeks on Mondays at 9am CET. Send us a message to join.

The goal: develop the first open source protocol to produce insulin simply and economically

Access to affordable insulin is not a given. Many people in poorer communities or developing countries have no way of getting appropriate treatment for diabetes. This leads to serious ilnesses such as blindness, amputations, cardiovascular disease and ultimately coma or death.

There is no generic insulin on the market and prices are kept high by patent strategies of the few companies that control the market. We're trying to change this by open sourcing the knowledge required to produce insulin.

As an obvious result this would allow production of cheaper insulin by generic suppliers. It might also enable home brewing of insulin or local microfactories in remote areas. Moreover, it can serve as a fertile soil for more open innovation and citizen science in research.

Still, the scope of this project is narrowly defined: develop and validate a production method for insulin. Patient testing and further engineering are not on the table before this important milestone.

The original Open Insulin team from Counter Culture Labs started out by attempting to modify E. Coli bacteria to produce the precursors of human insulin, which has proven successful. Next steps are purification and turning it into human insulin.

The actual lab work is done locally and the open conversation takes place online. This is the workspace for the Ghent group and we invite everyone to participate as we get the lab work underway.

Want to take part? Drop by at one of the open lab spaces in Oakland (US), Sydney (AUS) or Ghent (BE) or ping a team member to join the fortnightly conference call on Sunday/Monday.

To join this online workspace you can create an edgeryders account here. Edgeryders is a global network working to affect change in local and global environments. We use this open internet platform (self-hosted) to collaborate on different projects.

like0

Team meeting notes 12.04.17

Francis is new to the project and arrived a little earlier to give his input. He can help us with mass spectrometry and other analysis methods to determine if we’re working with insulin. He does have some technical questions about purity and the kind of buffer of the samples.

This is partially answered by the fact that we will start from the bacteria, so we do the extraction of the molecules and hence control the buffer and purity.

Open Insulin - Educational Outreach

Hi everyone!

I'd like to set up a discussion on the outreach aspect of the project. I feel like people have heard about insulin and diabetes and they vaguely know it has something to do with sugar and stabbing yourself (In Flanders, when people have diabetes, they have 'The Sugar').
So we have the opportunity to address that through this project.

The way I see it, the content would fall within these 3 categories and I think it would be cool to do one project in each:

Brainstorm notes 05.04.2017

We can have the bacteria soon already. Winnie has heard from CCL that they have a partner who has experience in shipping globally. BioFoundry confirms for their case.

We need to plan so that we are prepared to receive them. What is the minimum we need?

List:

  • Antibiotics

  • Glycerol

  • Medium (liquid/solid)

--> The above would account to <100€

Kickoff meeting notes

Winnie’s presentation

  • 400 million + diabetics
  • no generic insulin 
  • poorer communities have limited access
  • complications include blindness and amputations
  • patent strategies keep prices up. The industrial insulin patent is 90 years old; pharma reacts by tweaking patents (for example, they patent the delivery method)

No tasks have been added to this group.

Team meeting notes 12.04.17

Francis is new to the project and arrived a little earlier to give his input. He can help us with mass spectrometry and other analysis methods to determine if we’re working with insulin. He does have some technical questions about purity and the kind of buffer of the samples.

This is partially answered by the fact that we will start from the bacteria, so we do the extraction of the molecules and hence control the buffer and purity.

Open Insulin - Educational Outreach

Hi everyone!

I'd like to set up a discussion on the outreach aspect of the project. I feel like people have heard about insulin and diabetes and they vaguely know it has something to do with sugar and stabbing yourself (In Flanders, when people have diabetes, they have 'The Sugar').
So we have the opportunity to address that through this project.

The way I see it, the content would fall within these 3 categories and I think it would be cool to do one project in each:

Brainstorm notes 05.04.2017

We can have the bacteria soon already. Winnie has heard from CCL that they have a partner who has experience in shipping globally. BioFoundry confirms for their case.

We need to plan so that we are prepared to receive them. What is the minimum we need?

List:

  • Antibiotics

  • Glycerol

  • Medium (liquid/solid)

--> The above would account to <100€

Kickoff meeting notes

Winnie’s presentation

  • 400 million + diabetics
  • no generic insulin 
  • poorer communities have limited access
  • complications include blindness and amputations
  • patent strategies keep prices up. The industrial insulin patent is 90 years old; pharma reacts by tweaking patents (for example, they patent the delivery method)
No documents have been added to this group.
No wikis have been added to this group.

Recent activity in this group

Thu, 20/04/2017 - 10:07
Thu, 20/04/2017 - 10:04
Tue, 18/04/2017 - 21:30
Tue, 18/04/2017 - 19:25

Group contributors

Contributors

Organizers