I would keep everything in one wiki as long as possible, and heavily work with internal links to keep it readable and navigable. This can work well up to 500 works at least (as don in Autarky Library). Editing will not be comfortable at such a size, but that’s a secondary concern.
In current Discourse, it’s a bit tricky to get the structure of such a wiki right. Namely, only <h… id="heading--…">…</h…> HTML elements can be used to create a subpart marker link in such way that external links can directly point to one entry in the list.
For this wiki, I would probably create two literature lists: fiction and non-fiction. Order the list by title or lead author surname, and format the entries so that a list entry starts with that part, so that the alphabetic sorting is obvious. Then have several other lists and texts that point people to works in this large list via links, based on what they are looking for.
One list entry in the literature list could look like this:
<h4 id="heading--walkaway">"Walkaway", by Cory Doctorow <a href="#heading--walkaway">🔗</a></h4>
Depicts an economy entirely based on DIY production, […]
Rendering in Discourse:
"Walkaway", by Cory Doctorow 🔗
Depicts an economy entirely based on DIY production, […]
The link symbol allows to do “right click → Copy link address” to allow somebody to easily get the direct link to this list entry, to use inside the same wiki or in any external web resource.