I started this simple wiki for beginners and experts alike to get oriented in contributing to the Open Insulin project. For beginners it should be a starting point to learn more about the technology. It should help everyone better navigate the information we have archived on the Google Drive.
This wiki contains:
- How do I get involved?
- Research Status
- Technology Basics
- Where do I find information?
Anyone who wants to help build this can join in. SImple things you can do:
- Find good quality online educational material that offers an introduction to synthetic biology, molecular biology, protein engineering, genetics and other relevant fields. Add it to the 'Technology Basics' section with a short description containing what's it about and why people should use it.
- Help in organising information. Are you a pro in organising scientific articles and data? Great, we can use help with that! Get in touch with @WinniePoncelet .
- Add Frequently Asked Questions. Have you been asked about the project? Put the question and your answer in the FAQ!
1. How do I get involved?
You are a beginner or a (bio)scientist: everyone is welcome to join! We can use your brains, energy and creativity regardless of your prior knowledge.
As a beginner or non-bioscientist, you may be interested in learning more about the technology. It is super interesting stuff and it will also help you to contribute to the project at a technological level. Take a look at the technology basics below.
As a bioscientist trained in the field, you can jump right in. Take a look below at the research status and introduce yourself on the forum or at one of the live meetings (see introduction post for the latest info).
You can also help us by donating materials or money, and we’d be forever grateful! Get in touch to discuss how it could work.
2. Research status
Current step: awaiting the arrival of the plasmid samples from the team in Oakland.
Next step: use the plasmids to transform E. coli, in order to replicate the work of Oakland and set a reference point for further optimization.
Updates from the Oakland team can be found on their website.
3. Technology basics
MOOC on production of medicines, with insulin as a case. Not currently online but @arnepauwels has notes.
This MOOC on synthetic biology will require some additional study (eg. looking up terms on Wikipedia) but guides you through the basics.
MIT offers a very extensive range of biology courses (some of which are written in comic sans). One of them is this solid introduction to biology on edX. Choose recent courses, knowledge is outdated fast as the field changes rapidly.
Can anyone recommend other specific courses?
4. Where do I find information?
On the Google Drive, and we’re working on organizing it! (we’re limiting access to team members, get in touch if you’re interested).
- You're working open source, where's the data?
It is not currently openly available (see the discussion below).
- Are you going to inject hacked drugs into people?
No. The goal (for now) is a production protocol for the insulin molecule.